I guess the obvious question is the penetration standard for HPs reasonable? Since the gel represents muscle and not the hodgepodge of muscle, fat, bone and clothing comprising a human target real expansion is open to debate on all lighter loads, right? The problem with earlier HP rounds for .380 was lack of expansion, obviously the newer rounds like Hornady CD & Speer GoldDot solved the expansion issue, so really how much penetration is reasonable for HPs? The results did not surprise me, FMJ ammo should penetrate deeper. Using .380 for defense purposes I always had the mindset that 2-3 rounds should score hits before I expect an assailant to be disabled, and I would retain that expectation with FMJ or HPs. I tend to carry a .380 in the summer months as the lighter clothing people typically wear makes less fabric to punch through. I think 2-3 hits with .380 HPs will do the job, but it may make sense to burn through the HPs like Trap suggests, and since FMJ is cheaper than HPs there is some cost savings in future purchases.