I think it's going to require certain other circumstances falling into place, such as an economic collapse or partial collapse. Jefferson also noted, in the DoI, that experience has always shown people are inclined to endure injustice when doing so is not excessively onerous. The statists' mission is built on a cynical understanding of this tendency, but the statists have a tendency of their own, and it is one that will inevitably begin to weaken that other aforementioned tendency of the people to endure injustices. That the insults to the American traditions of individual liberty and free enterprise are now coming harder and faster may yet prove to be a major, if ironic, advantage. I also think any sort of collective resistance, when it comes, will be preceded by numerous unrelated instances of certain individuals who have reached a point where they feel like they have nothing left to lose. The statists' response to that will likely be to heap further injustices upon the citizenry.
And I do agree that resistance from states is what will begin the process of creating an air of legitimacy to the notion that the federal government cannot do whatever it wants just because it says it can. We're already starting to see this air of legitimacy, with various states passing laws about manufacture of firearms, light bulbs, border security, anti-Obamacare, and so on.