Cartilage Regenerating Stem-cell Gel?
Post by irondiopriest on Feb 9, 2010, 4:21pm
Having been told that it is a matter of time before my knees will need to be replaced (old football injuries) due to the near absence of cartilage beneath the patella, this is welcome news to me.... As long as no embryos are harvested for my benefit.
By Stimulating Stem Cells, Bioactive Nanogel Regenerates Cartilage in Joints
The body is a resilient biological structure, but there's one thing medical science, an increasing number of Baby Boomers, and the majority of professional athletes will all tell you: Take care of your joints, because once you burn up the cartilage you started with, you're not getting any more. But a breakthrough by Northwestern University scientists will now allow adult joints to naturally grow new cartilage for the very first time.
Unlike bone, muscle and other tissues in the body, cartilage that is damaged or worn away over time does not regenerate itself. The cartilage you have when you reach adulthood has to last you for life; if it doesn't, you can suffer debilitating joint pain or even osteoarthiritis, which is neither pleasant nor effectively treatable.
To stimulate the growth of type II collagen -- the main protein in the clean, smooth cartilage that caps bones where they make contact in joints -- the NU researchers created a bioactive nanogel that can be injected into the joint in a minimally invasive manner. The gel self-assmebles into a fibrous, solid extracellular matrix similar to what joint cells see in natural cartilage production. The gel also binds to one of the key growth factors for cartilage regeneration and keeps it localized in the damaged area. This stimulates the stem cells present in bone marrow that in turn activate type II collagen production naturally. The matrix slowly breaks down into nutrients as the natural cartilage builds up, eventually being replaced altogether by locally grown cartilage tissue.
The process has undergone successful animal testing, but its likely got a few more years of testing ahead of it before it could become commonplace. But the timing couldn't be better; an aging population means an increase in achy old joints. A fresh round of cartilage production could keep many of the more senior members of society in the workforce, on the golf course and out of orthopedic surgeon's office.
Re: Cartilage Regenerating Stem-cell Gel?
Post by pandora on Feb 9, 2010, 4:53pm
This is good news if it pans out. Athletes of many persuasions and ages, including weight-lifters, will benefit.
If anybody remembers Joe Bastardi, a well-known weather-guy, he is/was a competitive body-builder who cannot do chest presses any longer because he blew out his front delts/shoulder joints.
Timing .... aging population .... the statist medical care/population controllers are gonna be pissed. Bwaha.
Re: Cartilage Regenerating Stem-cell Gel?
Post by userinvisible on Feb 9, 2010, 4:56pm
Feb 9, 2010, 4:53pm, pandora wrote:
This is good news if it pans out. Athletes of many persuasions and ages, including weight-lifters, will benefit.
If anybody remembers Joe Bastardi, a well-known weather-guy, he is/was a competitive body-builder who cannot do chest presses any longer because he blew out his front delts/shoulder joints.
Timing .... aging population .... the statist medical care/population controllers are gonna be pissed. Bwaha.
Old paratroopers with bad knee's that try to shovel snow and blow out their back........
<raises hand>
Re: Cartilage Regenerating Stem-cell Gel?
Post by tenajrevilo on Feb 10, 2010, 5:20pm
This is good news for me as well, as I seem to be developing arthritis in my knees. Glucosamine and chondroitin can only take me so far, I think.....
Re: Cartilage Regenerating Stem-cell Gel?
Post by irondiopriest on Feb 10, 2010, 6:14pm
Feb 10, 2010, 5:20pm, tenajrevilo wrote:
This is good news for me as well, as I seem to be developing arthritis in my knees. Glucosamine and chondroitin can only take me so far, I think.....
I take G & C too. It can't regenerate cartilage, only slow it's loss.
Re: Cartilage Regenerating Stem-cell Gel?
Post by johnflorida on Feb 10, 2010, 7:06pm
Feb 10, 2010, 6:14pm, irondiopriest wrote:
Feb 10, 2010, 5:20pm, tenajrevilo wrote:
This is good news for me as well, as I seem to be developing arthritis in my knees. Glucosamine and chondroitin can only take me so far, I think.....
I take G & C too. It can't regenerate cartilage, only slow it's loss.
I have been following this for a while. IDP you need to see this.
http://www.youtube.com/watch?v=JiUh064xDSQhttp://www.youtube.com/watch?v=PaX3rMr0ICERe: Cartilage Regenerating Stem-cell Gel?
Post by irondiopriest on Feb 10, 2010, 7:13pm
Feb 10, 2010, 7:06pm, johnflorida wrote:
Feb 10, 2010, 6:14pm, irondiopriest wrote:
I take G & C too. It can't regenerate cartilage, only slow it's loss.
I have been following this for a while. IDP you need to see this.
http://www.youtube.com/watch?v=JiUh064xDSQhttp://www.youtube.com/watch?v=PaX3rMr0ICEThat's so cool. I would pay a generous sum to have my knees back without replacement surgery.
Re: Cartilage Regenerating Stem-cell Gel?
Post by johnflorida on Feb 10, 2010, 7:40pm
Feb 10, 2010, 7:13pm, irondiopriest wrote:
Feb 10, 2010, 7:06pm, johnflorida wrote:
I have been following this for a while. IDP you need to see this.
http://www.youtube.com/watch?v=JiUh064xDSQhttp://www.youtube.com/watch?v=PaX3rMr0ICEThat's so cool. I would pay a generous sum to have my knees back without replacement surgery.
Price it out and see what's what.
Re: Cartilage Regenerating Stem-cell Gel?
Post by tenajrevilo on Feb 11, 2010, 12:18pm
Feb 10, 2010, 6:14pm, irondiopriest wrote:
Feb 10, 2010, 5:20pm, tenajrevilo wrote:
This is good news for me as well, as I seem to be developing arthritis in my knees. Glucosamine and chondroitin can only take me so far, I think.....
I take G & C too. It can't regenerate cartilage, only slow it's loss.
Yes! Thank you. I figure I've probably got ten years before they really get bad, so hopefully all the bugs will bill worked out of this new treatment long before then.
Re: Cartilage Regenerating Stem-cell Gel?
Post by warpmine on Aug 16, 2010, 9:51pm
Rather than a new thread. something related to it, Of course I have to mention, as the clinic states that they're having a problem sudddenly with teh FDA now that Obamacare is on the march.
http://www.wnd.com/index.php?fa=PAGE.view&pageId=191177Yet another positive use for adult stem cells instead of killing of human embryos for havesting process.
Re: Cartilage Regenerating Stem-cell Gel?
Post by nolan on Aug 16, 2010, 10:07pm
Wow! The stuff they do now!
And I agree w/ the sentiment re: destroying a fetus to ease my pain. I can't tell you how little respect I have for Michael J. Fox since he became so vocal on the subject. Ruining another life, destroying it, in fact, because you were dealt a sh*tty hand isn't my idea of progress.
And I'll be first in line (I hope ) when it's available! I am not lookin' forward to getting stuck in a wheel chair in my 50's or 60's!
Re: Cartilage Regenerating Stem-cell Gel?
Post by libertasinfinitio on Aug 17, 2010, 6:42am
Huh, I got knee with crud floating around in it, sounds like a rattle when I flex it, wonder if thus could help.
And ditto on the embryo sentiment, adult cells and procedures like this are actually getting results, without adding accessory to murder into the mix.