We're already long over due for the New Madrid fault to give way. That will change the course of the Mississippi River as it has in the past.
Natural disasters much like installing an ineligible community agitator in the Presidency of the United States will continue just as the Earth will continue to reshape it's landscapes as it has for ions. I can't read into it more than that, however, looking at political events around the globe, I might be inclined to believe something's coming.